What is 21?
21 is a technique normally used in bicep curls, although it is possible to perform it in more exercises.
Here is an example of a set of 21's for the bicep curl exercise:
7 reps of bicep curl with the first half of the movement (from bottom to middle)
7 reps of bicep curl with the second half of the movement (from middle to above)
7 full bicep curl reps (normal, full movement)
All of this was done in a row, without rest, totaling a total of 21 repetitions.